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Leaky Gut Syndrome

Leaky Gut Syndrome Video

Delayed food related sensitivities begin in the gastro-intestinal tract when the intestinal lining becomes hyper-permeable. This problem is known as "leaky gut syndrome". Medically, it is defined as an increase in permeability of the intestinal mucosa to partially digested protein macromolecules, antigens and toxins. Recently, Zonulin, a protein found in the human gut, was discovered at the University of Maryland, by Dr. H. Fasano. This protein was originally discovered in high concentration in patients with acute Celiac Disease. It destroys or opens the tight junctions between mucosa cells of the gut, which causes an increased permeability and an increased absorption of partially digested proteins. The immunological reaction to these proteins in the liver initiate and perpetuate chronic food sensitivity. An increase in intestinal permeability or leaky gut is a common and very real problem. If the gut is not healthy, neither is the rest of the body. Escalating food sensitivities are among the many problems caused by a leaky gut. However, gas, bloating, abdominal pain, indigestion, alternating constipation and diarrhea or irritable bowel syndrome may not be all that's going on in the body. When the gut lining becomes inflamed or damaged the normal function of the gastro-intestinal tract is disrupted. Normally, the body recognizes and absorbs only amino acids, glucose and the short chain fatty acids, but with a leaky gut, large food antigens are absorbed into the body. The body's defense systems attack and the result is the production of antibodies against once harmless, innocuous foods. IgG antibodies and immune complexes are formed in the bloodstream and circulate.

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Immune Complex